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KRAS and BRAF mutations in patients with rectal cancer treated with preoperative chemoradiotherapy

BACKGROUND AND PURPOSE: KRAS and BRAF are mutated in 35% and 10% of colorectal cancers, respectively. However, data specifically for locally advanced rectal cancers are scarce, and the frequency of KRAS mutations in codons 61 and 146 remains to be established. MATERIALS AND METHODS: DNA was isolated...

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Bibliografiske detaljer
Udgivet i:Radiother Oncol
Main Authors: Gaedcke, Jochen, Grade, Marian, Jung, Klaus, Schirmer, Markus, Jo, Peter, Obermeyer, Christoph, Wolff, Hendrik A., Herrmann, Markus K., Beissbarth, Tim, Becker, Heinz, Ried, Thomas, Ghadimi, Michael
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7373270/
https://ncbi.nlm.nih.gov/pubmed/19913317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.radonc.2009.10.001
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