NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation

Acinar transdifferentiation toward a duct-like phenotype constitutes the defining response of acinar cells to external stress signals and is considered to be the initial step in pancreatic carcinogenesis. Despite the requirement for oncogenic Kras in pancreatic cancer (PDAC) development, oncogenic K...

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Detalhes bibliográficos
Publicado no:Stem Cells Int
Main Authors: Hessmann, Elisabeth, Zhang, Jin-San, Chen, Nai-Ming, Hasselluhn, Marie, Liou, Geou-Yarh, Storz, Peter, Ellenrieder, Volker, Billadeau, Daniel D., Koenig, Alexander
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677249/
https://ncbi.nlm.nih.gov/pubmed/26697077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5272498
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