NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation

Acinar transdifferentiation toward a duct-like phenotype constitutes the defining response of acinar cells to external stress signals and is considered to be the initial step in pancreatic carcinogenesis. Despite the requirement for oncogenic Kras in pancreatic cancer (PDAC) development, oncogenic K...

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Publicat a:Stem Cells Int
Autors principals: Hessmann, Elisabeth, Zhang, Jin-San, Chen, Nai-Ming, Hasselluhn, Marie, Liou, Geou-Yarh, Storz, Peter, Ellenrieder, Volker, Billadeau, Daniel D., Koenig, Alexander
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2016
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677249/
https://ncbi.nlm.nih.gov/pubmed/26697077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5272498
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