NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation

Acinar transdifferentiation toward a duct-like phenotype constitutes the defining response of acinar cells to external stress signals and is considered to be the initial step in pancreatic carcinogenesis. Despite the requirement for oncogenic Kras in pancreatic cancer (PDAC) development, oncogenic K...

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Bibliografski detalji
Izdano u:Stem Cells Int
Glavni autori: Hessmann, Elisabeth, Zhang, Jin-San, Chen, Nai-Ming, Hasselluhn, Marie, Liou, Geou-Yarh, Storz, Peter, Ellenrieder, Volker, Billadeau, Daniel D., Koenig, Alexander
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677249/
https://ncbi.nlm.nih.gov/pubmed/26697077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5272498
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