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Glycogen synthase kinase-3β ablation limits pancreatitis induced acinar-to-ductal metaplasia.
Acinar-to-ductal metaplasia (ADM) is a reversible epithelial trans-differentiation process that occurs in response to acute inflammation. ADM can rapidly progress toward pre-malignant pancreatic intraepithelial neoplasia (PanIN) lesions in the presence of mutant KRas and ultimately pancreatic adenoc...
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| Publicado no: | J Pathol |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6042855/ https://ncbi.nlm.nih.gov/pubmed/28639695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4928 |
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