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Paracrine Secretion of TGF-β by Ductal Cells Promotes Acinar-to-Ductal Metaplasia in Cultured Human Exocrine Pancreas Tissues

OBJECTIVE: We aimed to evaluate the contribution of acinar-to-ductal metaplasia (ADM) to the accumulation of cells with a ductal phenotype in cultured human exocrine pancreatic tissues and reveal the underlying mechanism. METHOD: We sorted and cultured viable cell populations in human exocrine pancr...

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Detalhes bibliográficos
Publicado no:Pancreas
Main Authors: Akanuma, Naoki, Liu, Jun, Liou, Geou-Yarh, Yin, Xue, Bejar, Kaitlyn R., Liu, Chengyang, Sun, Luzhe, Storz, Peter, Wang, Pei
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192250/
https://ncbi.nlm.nih.gov/pubmed/28902792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPA.0000000000000913
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