TGF-β1 promotes acinar to ductal metaplasia of human pancreatic acinar cells

Animal studies suggest that pancreatitis-induced acinar-to-ductal metaplasia (ADM) is a key event for pancreatic ductal adenocarcinoma (PDAC) initiation. However, there has not been an adequate system to explore the mechanisms of human ADM induction. We have developed a flow cytometry-based, high re...

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Vydáno v:Sci Rep
Hlavní autoři: Liu, Jun, Akanuma, Naoki, Liu, Chengyang, Naji, Ali, Halff, Glenn A., Washburn, William K., Sun, Luzhe, Wang, Pei
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4971483/
https://ncbi.nlm.nih.gov/pubmed/27485764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep30904
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