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Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias

Telomeres protect against chromosomal breakage, fusion, and interchromosome bridges during cell division. Shortened telomeres have been observed in the lowest grade of pancreatic intraepithelial neoplasia. Genetically engineered mouse models of pancreatic neoplasia develop acinar-to-ductal metaplasi...

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Bibliografski detalji
Glavni autori: Hong, Seung-Mo, Heaphy, Christopher M., Shi, Chanjuan, Eo, Soo-Heang, Cho, HyungJun, Meeker, Alan K., Eshleman, James R., Hruban, Ralph H., Goggins, Michael
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166222/
https://ncbi.nlm.nih.gov/pubmed/20871595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.181
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