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Telomeres are shortened in acinar-to-ductal metaplasia lesions associated with pancreatic intraepithelial neoplasia but not in isolated acinar-to-ductal metaplasias

Telomeres protect against chromosomal breakage, fusion, and interchromosome bridges during cell division. Shortened telomeres have been observed in the lowest grade of pancreatic intraepithelial neoplasia. Genetically engineered mouse models of pancreatic neoplasia develop acinar-to-ductal metaplasi...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hong, Seung-Mo, Heaphy, Christopher M., Shi, Chanjuan, Eo, Soo-Heang, Cho, HyungJun, Meeker, Alan K., Eshleman, James R., Hruban, Ralph H., Goggins, Michael
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3166222/
https://ncbi.nlm.nih.gov/pubmed/20871595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/modpathol.2010.181
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