Reg proteins promote acinar-to-ductal metaplasia and act as novel diagnostic and prognostic markers in pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive malignant tumor. Acinar-to-ductal metaplasia (ADM) and pancreatic intraepithelial neoplasia (PanIN) are both precursor lesions that lead to the development of PDAC. Reg family proteins (Reg1A, 1B, 3A/G, 4) are a group of calcium-dependen...

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Vydáno v:Oncotarget
Hlavní autoři: Li, Qing, Wang, Hao, Zogopoulos, George, Shao, Qin, Dong, Kun, Lv, Fudong, Nwilati, Karam, Gui, Xian-yong, Cuggia, Adeline, Liu, Jun-Li, Gao, Zu-hua
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2016
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363625/
https://ncbi.nlm.nih.gov/pubmed/27788482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.12834
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