Maintenance of Acinar Cell Organization is Critical to Preventing Kras-Induced Acinar-Ductal Metaplasia

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal cancers owing to a number of characteristics including difficulty in establishing early diagnosis and the absence of effective therapeutic regimens. A large number of genetic alterations have been ascribed to PDAC with mutations in th...

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Autori principali: Shi, Guanglu, DiRenzo, Daniel, Qu, Chunjing, Barney, Darci, Miley, David, Konieczny, Stephen F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3435479/
https://ncbi.nlm.nih.gov/pubmed/22665051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.210
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