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Slug inhibits pancreatic cancer initiation by blocking Kras-induced acinar-ductal metaplasia
Cells in the pancreas that have undergone acinar-ductal metaplasia (ADM) can transform into premalignant cells that can eventually become cancerous. Although the epithelial-mesenchymal transition regulator Snail (Snai1) can cooperate with Kras in acinar cells to enhance ADM development, the contribu...
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| Pubblicato in: | Sci Rep |
|---|---|
| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4929679/ https://ncbi.nlm.nih.gov/pubmed/27364947 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep29133 |
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