Ładuje się......
BET inhibitors block pancreatic stellate cell collagen I production and attenuate fibrosis in vivo
The fibrotic reaction, which can account for over 70%–80% of the tumor mass, is a characteristic feature of human pancreatic ductal adenocarcinoma (PDAC) tumors. It is associated with activation and proliferation of pancreatic stellate cells (PSCs), which are key regulators of collagen I production...
Zapisane w:
| Wydane w: | JCI Insight |
|---|---|
| Główni autorzy: | , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2017
|
| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5291732/ https://ncbi.nlm.nih.gov/pubmed/28194432 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.88032 |
| Etykiety: |
Dodaj etykietę
Nie ma etykietki, Dołącz pierwszą etykiete!
|