Interplay between interferon regulatory factor 1 and BRD4 in the regulation of PD-L1 in pancreatic stellate cells

The fibrotic reaction is a characteristic feature of human pancreatic ductal adenocarcinoma (PDAC) tumors. It is associated with activation and proliferation of pancreatic stellate cells (PSCs), which are key regulators of fibrosis in vivo. While there is increasing interest in the regulation of PD-...

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Publicado no:Sci Rep
Main Authors: Ebine, Kazumi, Kumar, Krishan, Pham, Thao N., Shields, Mario A., Collier, Katharine A., Shang, Meng, DeCant, Brian T., Urrutia, Raul, Hwang, Rosa F., Grimaldo, Sam, Principe, Daniel R., Grippo, Paul J., Bentrem, David J., Munshi, Hidayatullah G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6125340/
https://ncbi.nlm.nih.gov/pubmed/30185888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-31658-1
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