SIRT3 and SIRT4 are mitochondrial tumor suppressor proteins that connect mitochondrial metabolism and carcinogenesis

Por Zhu, Yueming, Yan, Yufan, Principe, Daniel R, Zou, Xianghui, Vassilopoulos, Athanassios, Gius, David
Publicado em 2014

Utilizing past and present mouse systems to engineer more relevant pancreatic cancer models

Por DeCant, Brian T., Principe, Daniel R., Guerra, Carmen, Pasca di Magliano, Marina, Grippo, Paul J.
Publicado no Front Physiol (2014)

TGF-β: Duality of Function Between Tumor Prevention and Carcinogenesis

Por Principe, Daniel R., Doll, Jennifer A., Bauer, Jessica, Jung, Barbara, Munshi, Hidayatullah G., Bartholin, Laurent, Pasche, Boris, Lee, Chung, Grippo, Paul J.
Publicado em 2014

Ablation of 5-lipoxygenase mitigates pancreatic lesion development

Por Knab, Lawrence M., Schultz, Michelle, Principe, Daniel R., Mascarinas, Windel E., Gounaris, Elias, Munshi, Hidayatullah G., Grippo, Paul J., Bentrem, David J.
Publicado no J Surg Res (2014)

Genetically Induced Tumors in the Oncopig Model Invoke an Antitumor Immune Response Dominated by Cytotoxic CD8β(+) T Cells and Differentiated γδ T Cells Alongside a Regulatory Resp...

Por Overgaard, Nana H., Principe, Daniel R., Schachtschneider, Kyle M., Jakobsen, Jeanne Toft, Rund, Laurie A., Grippo, Paul J., Schook, Lawrence B., Jungersen, Gregers
Publicado no Front Immunol (2018)

Activin and TGFβ use diverging mitogenic signaling in advanced colon cancer

Por Bauer, Jessica, Ozden, Ozkan, Akagi, Naomi, Carroll, Timothy, Principe, Daniel R., Staudacher, Jonas J., Spehlmann, Martina E., Eckmann, Lars, Grippo, Paul J., Jung, Barbara
Publicado no Mol Cancer (2015)

Characterization of mouse models of early pancreatic lesions induced by alcohol and chronic pancreatitis

Por Xu, Shiping, Chheda, Chintan, Ouhaddi, Yassine, Benhaddou, Hajar, Bourhim, Mouloud, Grippo, Paul J., Principe, Daniel R., Mascariñas, Emman, DeCant, Brian, Tsukamoto, Hidekazu, Pandol, Stephen J., Edderkaoui, Mouad
Publicado no Pancreas (2015)

SIRT2 deletion enhances KRAS-induced tumorigenesis in vivo by regulating K147 acetylation status

Por Song, Ha Yong, Biancucci, Marco, Kang, Hong-Jun, O'Callaghan, Carol, Park, Seong-Hoon, Principe, Daniel R., Jiang, Haiyan, Yan, Yufan, Satchell, Karla Fullner, Raparia, Kirtee, Gius, David, Vassilopoulos, Athanassios
Publicado no Oncotarget (2016)

HDAC3 mediates smoking-induced pancreatic cancer

Por Edderkaoui, Mouad, Xu, Shiping, Chheda, Chintan, Morvaridi, Susan, Hu, Robert W., Grippo, Paul J., Mascariñas, Emman, Principe, Daniel R., Knudsen, Beatrice, Xue, Jing, Habtezion, Aida, Uyeminami, Dale, Pinkerton, Kent E., Pandol, Stephen J.
Publicado no Oncotarget (2016)

SIRT2-mediated deacetylation and tetramerization of pyruvate kinase directs glycolysis and tumor growth

Por Park, Seong-Hoon, Ozden, Ozkan, Liu, Guoxiang, Song, Ha Yong, Zhu, Yueming, Yan, Yufan, Zou, Xianghui, Kang, Hong-Jun, Jiang, Haiyan, Principe, Daniel R., Cha, Yong-Il, Roh, Meejeon, Vassilopoulos, Athanassios, Gius, David
Publicado no Cancer Res (2016)

A validated, transitional and translational porcine model of hepatocellular carcinoma

Por Schachtschneider, Kyle M., Schwind, Regina M., Darfour-Oduro, Kwame A., De, Arun K., Rund, Lauretta A., Singh, Kuldeep, Principe, Daniel R., Guzman, Grace, Ray, Charles E., Ozer, Howard, Gaba, Ron C., Schook, Lawrence B.
Publicado no Oncotarget (2017)

TGFβ signaling in the pancreatic tumor microenvironment promotes fibrosis and immune evasion to facilitate tumorigenesis

Por Principe, Daniel R., DeCant, Brian, Mascariñas, Emman, Wayne, Elizabeth A., Diaz, Andrew M., Diaz, Naomi, Hwang, Rosa, Pasche, Boris, Dawson, David W., Fang, Deyu, Bentrem, David J., Munshi, Hidayatullah G., Jung, Barbara, Grippo, Paul J.
Publicado no Cancer Res (2016)

PEDF inhibits pancreatic tumorigenesis by attenuating the fibro-inflammatory reaction

Por Principe, Daniel R., DeCant, Brian, Diaz, Andrew M., Mangan, Riley J., Hwang, Rosa, Lowy, Andrew, Shetuni, Brandon B., Sreekumar, Bharath K., Chung, Chuhan, Bentrem, David J., Munshi, Hidayatullah G., Jung, Barbara, Grippo, Paul J., Bishehsari, Faraz
Publicado no Oncotarget (2016)

Loss of TGFβ signaling promotes colon cancer progression and tumor-associated inflammation

Por Principe, Daniel R., DeCant, Brian, Staudacher, Jonas, Vitello, Dominic, Mangan, Riley J., Wayne, Elizabeth A., Mascariñas, Emman, Diaz, Andrew M., Bauer, Jessica, McKinney, Ronald D., Khazaie, Khashayarsha, Pasche, Boris, Dawson, David W., Munshi, Hidayatullah G., Grippo, Paul J., Jung, Barbara
Publicado no Oncotarget (2016)

The Oncopig Cancer Model: An Innovative Large Animal Translational Oncology Platform

Por Schachtschneider, Kyle M., Schwind, Regina M., Newson, Jordan, Kinachtchouk, Nickolas, Rizko, Mark, Mendoza-Elias, Nasya, Grippo, Paul, Principe, Daniel R., Park, Alex, Overgaard, Nana H., Jungersen, Gregers, Garcia, Kelly D., Maker, Ajay V., Rund, Laurie A., Ozer, Howard, Gaba, Ron C., Schook, Lawrence B.
Publicado no Front Oncol (2017)