TGF-β: Duality of Function Between Tumor Prevention and Carcinogenesis

Several mechanisms underlying tumor progression have remained elusive, particularly in relation to transforming growth factor beta (TGF-β). Although TGF-β initially inhibits epithelial growth, it appears to promote the progression of advanced tumors. Defects in normal TGF-β pathways partially explai...

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Detalhes bibliográficos
Main Authors: Principe, Daniel R., Doll, Jennifer A., Bauer, Jessica, Jung, Barbara, Munshi, Hidayatullah G., Bartholin, Laurent, Pasche, Boris, Lee, Chung, Grippo, Paul J.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2014
Assuntos:
Review
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3952197/
https://ncbi.nlm.nih.gov/pubmed/24511106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt369
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