Loss of TGFβ signaling promotes colon cancer progression and tumor-associated inflammation

TGFβ has both tumor suppressive and tumor promoting effects in colon cancer. Also, TGFβ can affect the extent and composition of inflammatory cells present in tumors, contextually promoting and inhibiting inflammation. While colon tumors display intratumoral inflammation, the contributions of TGFβ t...

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Publicado en:Oncotarget
Autores principales: Principe, Daniel R., DeCant, Brian, Staudacher, Jonas, Vitello, Dominic, Mangan, Riley J., Wayne, Elizabeth A., Mascariñas, Emman, Diaz, Andrew M., Bauer, Jessica, McKinney, Ronald D., Khazaie, Khashayarsha, Pasche, Boris, Dawson, David W., Munshi, Hidayatullah G., Grippo, Paul J., Jung, Barbara
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354798/
https://ncbi.nlm.nih.gov/pubmed/27270652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9830
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