Loss of TGFβ signaling promotes colon cancer progression and tumor-associated inflammation

TGFβ has both tumor suppressive and tumor promoting effects in colon cancer. Also, TGFβ can affect the extent and composition of inflammatory cells present in tumors, contextually promoting and inhibiting inflammation. While colon tumors display intratumoral inflammation, the contributions of TGFβ t...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Principe, Daniel R., DeCant, Brian, Staudacher, Jonas, Vitello, Dominic, Mangan, Riley J., Wayne, Elizabeth A., Mascariñas, Emman, Diaz, Andrew M., Bauer, Jessica, McKinney, Ronald D., Khazaie, Khashayarsha, Pasche, Boris, Dawson, David W., Munshi, Hidayatullah G., Grippo, Paul J., Jung, Barbara
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354798/
https://ncbi.nlm.nih.gov/pubmed/27270652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9830
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