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Effects of Activin and TGFβ on p21 in Colon Cancer
Activin and TGFβ share SMAD signaling and colon cancers can inactivate either pathway alone or simultaneously. The differential effects of activin and TGFβ signaling in colon cancer have not been previously dissected. A key downstream target of TGFβ signaling is the cdk2 inhibitor p21 (p21(cip1/waf1...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3383701/ https://ncbi.nlm.nih.gov/pubmed/22761777 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0039381 |
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