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Ablation of 5-lipoxygenase mitigates pancreatic lesion development
BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC), which continues to have a dismal prognosis, is associated with a pronounced fibro-inflammatory response. Inflammation in vivo can be mediated by 5-lipoxygenase (5LO), an enzyme that converts omega-6 fatty acids to eicosanoids, including leukotrien...
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| Publicado no: | J Surg Res |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4843112/ https://ncbi.nlm.nih.gov/pubmed/25454978 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jss.2014.10.021 |
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