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Cancer Cell Invasion in Three-dimensional Collagen Is Regulated Differentially by Gα(13) Protein and Discoidin Domain Receptor 1-Par3 Protein Signaling

Cancer cells can invade in three-dimensional collagen as single cells or as a cohesive group of cells that require coordination of cell-cell junctions and the actin cytoskeleton. To examine the role of Gα(13), a G(12) family heterotrimeric G protein, in regulating cellular invasion in three-dimensio...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Chow, Christina R., Ebine, Kazumi, Knab, Lawrence M., Bentrem, David J., Kumar, Krishan, Munshi, Hidayatullah G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722444/
https://ncbi.nlm.nih.gov/pubmed/26589794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.669606
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