REG3A/REG3B promotes acinar to ductal metaplasia through binding to EXTL3 and activating the RAS-RAF-MEK-ERK signaling pathway

Persistent acinar to ductal metaplasia (ADM) is a recently recognized precursor of pancreatic ductal adenocarcinoma (PDAC). Here we show that the ADM area of human pancreas tissue adjacent to PDAC expresses significantly higher levels of regenerating protein 3A (REG3A). Exogenous REG3A and its mouse...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:Commun Biol
Asıl Yazarlar: Zhang, Huairong, Corredor, Andrea Liliam Gomez, Messina-Pacheco, Julia, Li, Qing, Zogopoulos, George, Kaddour, Nancy, Wang, Yifan, Shi, Bing-yin, Gregorieff, Alex, Liu, Jun-li, Gao, Zu-hua
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group UK 2021
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC8184755/
https://ncbi.nlm.nih.gov/pubmed/34099862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-021-02193-z
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller