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Mimicking and manipulating pancreatic acinar-to-ductal metaplasia in 3-dimensional cell culture

The differentiation of acinar cells to ductal cells during pancreatitis and in the early development of pancreatic cancer is a key process that requires further study. To understand the mechanisms regulating acinar-to-ductal metaplasia (ADM), ex vivo 3D culture and differentiation of primary acinar...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Martinez, Alicia K. Fleming, Storz, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6922010/
https://ncbi.nlm.nih.gov/pubmed/30799859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59096
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