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Mimicking and manipulating pancreatic acinar-to-ductal metaplasia in 3-dimensional cell culture

The differentiation of acinar cells to ductal cells during pancreatitis and in the early development of pancreatic cancer is a key process that requires further study. To understand the mechanisms regulating acinar-to-ductal metaplasia (ADM), ex vivo 3D culture and differentiation of primary acinar...

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Библиографические подробности
Опубликовано в: :J Vis Exp
Главные авторы: Martinez, Alicia K. Fleming, Storz, Peter
Формат: Artigo
Язык:Inglês
Опубликовано: 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6922010/
https://ncbi.nlm.nih.gov/pubmed/30799859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/59096
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