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Acinar cell plasticity and development of pancreatic ductal adenocarcinoma

Acinar cells in the adult pancreas show high plasticity and can undergo transdifferentiation to a progenitor-like cell type with ductal characteristics. This process, termed acinar-to-ductal metaplasia (ADM), is an important feature facilitating pancreas regeneration after injury. Data from animal m...

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Bibliografische gegevens
Gepubliceerd in:Nat Rev Gastroenterol Hepatol
Hoofdauteur: Storz, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6036907/
https://ncbi.nlm.nih.gov/pubmed/28270694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrgastro.2017.12
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