NFATc4 Regulates Sox9 Gene Expression in Acinar Cell Plasticity and Pancreatic Cancer Initiation

Acinar transdifferentiation toward a duct-like phenotype constitutes the defining response of acinar cells to external stress signals and is considered to be the initial step in pancreatic carcinogenesis. Despite the requirement for oncogenic Kras in pancreatic cancer (PDAC) development, oncogenic K...

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Bibliografiske detaljer
Udgivet i:Stem Cells Int
Main Authors: Hessmann, Elisabeth, Zhang, Jin-San, Chen, Nai-Ming, Hasselluhn, Marie, Liou, Geou-Yarh, Storz, Peter, Ellenrieder, Volker, Billadeau, Daniel D., Koenig, Alexander
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4677249/
https://ncbi.nlm.nih.gov/pubmed/26697077
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/5272498
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