More Paths to PI3Kγ

ανά Stephens, Len, Hawkins, Phillip
Έκδοση 2013

9. Successful use of IL-6 pathway blockade to treat autoinflammation occurring in the context of a novel TNFRS1A gene mutation

ανά Dyke, Bernard, Gordon, Caroline, Hawkins, Phillip, Tosounidou, Sofia
Τόπος έκδοσης Rheumatol Adv Pract (2019)

How is the acyl chain composition of phosphoinositides created and does it matter?

ανά Barneda, David, Cosulich, Sabina, Stephens, Len, Hawkins, Phillip
Τόπος έκδοσης Biochem Soc Trans (2019)

Class (I) Phosphoinositide 3-Kinases in the Tumor Microenvironment

ανά Gyori, David, Chessa, Tamara, Hawkins, Phillip T., Stephens, Len R.
Τόπος έκδοσης Cancers (Basel) (2017)

3D time series analysis of cell shape using Laplacian approaches

ανά Du, Cheng-Jin, Hawkins, Phillip T, Stephens, Len R, Bretschneider, Till
Έκδοση 2013

PtdIns3P binding to the PX domain of p40(phox) is a physiological signal in NADPH oxidase activation

ανά Ellson, Chris, Davidson, Keith, Anderson, Karen, Stephens, Len R, Hawkins, Phillip T
Έκδοση 2006

Investigating the effect of arachidonate supplementation on the phosphoinositide content of MCF10a breast epithelial cells

ανά Anderson, Karen E., Juvin, Veronique, Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T.
Τόπος έκδοσης Adv Biol Regul (2016)

Mechanism of the regulation of type IB phosphoinositide 3OH-kinase byG-protein betagamma subunits.

ανά Krugmann, Sonja, Cooper, Matthew A, Williams, Dudley H, Hawkins, Phillip T, Stephens, Len R
Έκδοση 2002

Phosphatidylinositol 3-kinase-γ activates Bruton’s tyrosine kinase in concert with Src family kinases

ανά Li, Zuomei, Wahl, Matthew I., Eguinoa, Alicia, Stephens, Leonard R., Hawkins, Phillip T., Witte, Owen N.
Έκδοση 1997

Neutrophils from p40(phox−/−) mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing

ανά Ellson, Chris D., Davidson, Keith, Ferguson, G. John, O'Connor, Rod, Stephens, Len R., Hawkins, Phillip T.
Έκδοση 2006

Perturbations of PIP3 signalling trigger a global remodelling of mRNA landscape and reveal a transcriptional feedback loop

ανά Kiselev, Vladimir Yu., Juvin, Veronique, Malek, Mouhannad, Luscombe, Nicholas, Hawkins, Phillip, Novère, Nicolas Le, Stephens, Len
Τόπος έκδοσης Nucleic Acids Res (2015)

Phosphoproteomic Analyses of Interleukin 2 Signaling Reveal Integrated JAK Kinase-Dependent and -Independent Networks in CD8(+) T Cells

ανά Ross, Sarah H., Rollings, Christina, Anderson, Karen E., Hawkins, Phillip T., Stephens, Len R., Cantrell, Doreen A.
Τόπος έκδοσης Immunity (2016)

Lysophosphatidylinositol-Acyltransferase-1 (LPIAT1) Is Required to Maintain Physiological Levels of PtdIns and PtdInsP(2) in the Mouse

ανά Anderson, Karen E., Kielkowska, Anna, Durrant, Tom N., Juvin, Veronique, Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T.
Έκδοση 2013

Frontline Science: TNF‐α and GM‐CSF1 priming augments the role of SOS1/2 in driving activation of Ras, PI3K‐γ, and neutrophil proinflammatory responses

ανά Suire, Sabine, Baltanas, Fernando C., Segonds‐Pichon, Anne, Davidson, Keith, Santos, Eugenio, Hawkins, Phillip T., Stephens, Len R.
Τόπος έκδοσης J Leukoc Biol (2019)

Phosphorylation of threonine 154 in p40(phox) is an important physiological signal for activation of the neutrophil NADPH oxidase

ανά Chessa, Tamara A. M., Anderson, Karen E., Hu, Yanhua, Xu, Qingbo, Rausch, Oliver, Stephens, Len R., Hawkins, Phillip T.
Έκδοση 2010

Dictyostelium uses ether-linked inositol phospholipids for intracellular signalling

ανά Clark, Jonathan, Kay, Robert R, Kielkowska, Anna, Niewczas, Izabella, Fets, Louise, Oxley, David, Stephens, Len R, Hawkins, Phillip T
Τόπος έκδοσης EMBO J (2014)

PI3K regulates integrin-dependent processes in neutrophils by signalling through its effector ARAP3

ανά Gambardella, Laure, Anderson, Karen E., Jakus, Zoltán, Kovács, Miklós, Voigt, Susann, Hawkins, Phillip T., Stephens, Len, Mócsai, Attila, Vermeren, Sonja
Έκδοση 2012

Structure of Lipid Kinase p110β/p85β Elucidates an Unusual SH2-Domain-Mediated Inhibitory Mechanism

ανά Zhang, Xuxiao, Vadas, Oscar, Perisic, Olga, Anderson, Karen E., Clark, Jonathan, Hawkins, Phillip T., Stephens, Len R., Williams, Roger L.
Έκδοση 2011

Two distinct functions for PI3-kinases in macropinocytosis

ανά Hoeller, Oliver, Bolourani, Parvin, Clark, Jonathan, Stephens, Len R., Hawkins, Phillip T., Weiner, Orion D., Weeks, Gerald, Kay, Robert R.
Έκδοση 2013

In B cells, phosphatidylinositol 5-phosphate 4-kinase–α synthesizes PI(4,5)P(2) to impact mTORC2 and Akt signaling

ανά Bulley, Simon J., Droubi, Alaa, Clarke, Jonathan H., Anderson, Karen E., Stephens, Len R., Hawkins, Phillip T., Irvine, Robin F.
Τόπος έκδοσης Proc Natl Acad Sci U S A (2016)