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How is the acyl chain composition of phosphoinositides created and does it matter?

The phosphoinositide (PIPn) family of signalling phospholipids are central regulators in membrane cell biology. Their varied functions are based on the phosphorylation pattern of their inositol ring, which can be recognized by selective binding domains in their effector proteins and be modified by a...

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Bibliographic Details
Published in:Biochem Soc Trans
Main Authors: Barneda, David, Cosulich, Sabina, Stephens, Len, Hawkins, Phillip
Format: Artigo
Language:Inglês
Published: Portland Press Ltd. 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6824679/
https://ncbi.nlm.nih.gov/pubmed/31657437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20190205
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