Signaling via Class IA Phosphoinositide 3-Kinases (PI3K) in Human, Breast-Derived Cell Lines

We have addressed the differential roles of class I Phosphoinositide 3-kinases (PI3K) in human breast-derived MCF10a (and iso-genetic derivatives) and MDA-MB 231 and 468 cells. Class I PI3Ks are heterodimers of p110 catalytic (α, β, δ and γ) and p50–101 regulatory subunits and make the signaling lip...

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Detalhes bibliográficos
Main Authors: Juvin, Veronique, Malek, Mouhannad, Anderson, Karen E., Dion, Carine, Chessa, Tamara, Lecureuil, Charlotte, Ferguson, G. John, Cosulich, Sabina, Hawkins, Phillip T., Stephens, Len R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3790768/
https://ncbi.nlm.nih.gov/pubmed/24124465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0075045
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