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PtdIns3P binding to the PX domain of p40(phox) is a physiological signal in NADPH oxidase activation
The production of reactive oxygen species by the NADPH oxidase complex of phagocytes plays a critical role in our defence against bacterial and fungal infections. The PX domains of two oxidase components, p47(phox) and p40(phox), are known to bind phosphoinositide products of PI3Ks but the physiolog...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1589987/ https://ncbi.nlm.nih.gov/pubmed/16990793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601346 |
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