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Neutrophils from p40(phox−/−) mice exhibit severe defects in NADPH oxidase regulation and oxidant-dependent bacterial killing
The generation of reactive oxygen species (ROS) by the reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex plays a critical role in the antimicrobial functions of the phagocytic cells of the immune system. The catalytic core of this oxidase consists of a complex between gp91(...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Rockefeller University Press
2006
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118373/ https://ncbi.nlm.nih.gov/pubmed/16880254 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052069 |
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