PtdIns(3)P-DEPENDENT AND INDEPENDENT FUNCTIONS OF p40PHOX IN ACTIVATION OF THE NEUTROPHIL NADPH OXIDASE

In response to bacterial infection, the neutrophil NADPH oxidase assembles on phagolysosomes to catalyze the transfer of electrons from NADPH to oxygen, forming superoxide and downstream reactive oxygen species (ROS). The active oxidase is composed of a membrane-bound cytochrome together with three...

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Bibliographic Details
Main Authors: Bissonnette, Sarah A., Glazier, Christina M., Stewart, Mary Q., Brown, Glenn E., Ellson, Chris D., Yaffe, Michael B.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2755574/
https://ncbi.nlm.nih.gov/pubmed/18029359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M706639200
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