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p47(phox) Phox Homology Domain Regulates Plasma Membrane but Not Phagosome Neutrophil NADPH Oxidase Activation

The assembly of cytosolic subunits p47(phox), p67(phox), and p40(phox) with flavocytochrome b(558) at the membrane is required for activating the neutrophil NADPH oxidase that generates superoxide for microbial killing. The p47(phox) subunit plays a critical role in oxidase assembly. Recent studies...

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Detalhes bibliográficos
Main Authors: Li, Xing Jun, Marchal, Christophe C., Stull, Natalie D., Stahelin, Robert V., Dinauer, Mary C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966130/
https://ncbi.nlm.nih.gov/pubmed/20817944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164475
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