p47(phox) Phox Homology Domain Regulates Plasma Membrane but Not Phagosome Neutrophil NADPH Oxidase Activation

The assembly of cytosolic subunits p47(phox), p67(phox), and p40(phox) with flavocytochrome b(558) at the membrane is required for activating the neutrophil NADPH oxidase that generates superoxide for microbial killing. The p47(phox) subunit plays a critical role in oxidase assembly. Recent studies...

Full description

Saved in:
Bibliographic Details
Main Authors: Li, Xing Jun, Marchal, Christophe C., Stull, Natalie D., Stahelin, Robert V., Dinauer, Mary C.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2010
Subjects:
Membrane Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966130/
https://ncbi.nlm.nih.gov/pubmed/20817944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.164475
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items