Phosphorylation of p22(phox) on Threonine 147 Enhances NADPH Oxidase Activity by Promoting p47(phox) Binding

NADPH oxidase comprises both cytosolic and membrane-bound subunits, which, when assembled and activated, initiate the transfer of electrons from NADPH to molecular oxygen to form superoxide. This activity, known as the respiratory burst, is extremely important in the innate immune response as indica...

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Bibliografiske detaljer
Main Authors: Lewis, Eric M., Sergeant, Susan, Ledford, Bill, Stull, Natalie, Dinauer, Mary C., McPhail, Linda C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2010
Fag:
Mechanisms of Signal Transduction
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823407/
https://ncbi.nlm.nih.gov/pubmed/19948736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.030643
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