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Phosphorylation of p22(phox) on Threonine 147 Enhances NADPH Oxidase Activity by Promoting p47(phox) Binding
NADPH oxidase comprises both cytosolic and membrane-bound subunits, which, when assembled and activated, initiate the transfer of electrons from NADPH to molecular oxygen to form superoxide. This activity, known as the respiratory burst, is extremely important in the innate immune response as indica...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2823407/ https://ncbi.nlm.nih.gov/pubmed/19948736 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.030643 |
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