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A Fluorescently Tagged C-Terminal Fragment of p47(phox) Detects NADPH Oxidase Dynamics during Phagocytosis

The assembly of cytosolic p47(phox) and p67(phox) with flavocytochrome b(558) at the membrane is crucial for activating the leukocyte NADPH oxidase that generates superoxide for microbial killing. p47(phox) and p67(phox) are linked via a high-affinity, tail-to-tail interaction involving a proline-ri...

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Bibliografiske detaljer
Main Authors: Li, Xing Jun, Tian, Wei, Stull, Natalie D., Grinstein, Sergio, Atkinson, Simon, Dinauer, Mary C.
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2649267/
https://ncbi.nlm.nih.gov/pubmed/19129478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0620
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