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A Fluorescently Tagged C-Terminal Fragment of p47(phox) Detects NADPH Oxidase Dynamics during Phagocytosis
The assembly of cytosolic p47(phox) and p67(phox) with flavocytochrome b(558) at the membrane is crucial for activating the leukocyte NADPH oxidase that generates superoxide for microbial killing. p47(phox) and p67(phox) are linked via a high-affinity, tail-to-tail interaction involving a proline-ri...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
The American Society for Cell Biology
2009
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2649267/ https://ncbi.nlm.nih.gov/pubmed/19129478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-06-0620 |
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