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The phosphoinositide-binding protein p40(phox) activates the NADPH oxidase during FcγIIA receptor–induced phagocytosis
Superoxide produced by the phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is essential for host defense. Enzyme activation requires translocation of p67(phox), p47(phox), and Rac-GTP to flavocytochrome b (558) in phagocyte membranes. To examine the regulation of phagoc...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2118377/ https://ncbi.nlm.nih.gov/pubmed/16880255 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052085 |
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