The phosphoinositide-binding protein p40(phox) activates the NADPH oxidase during FcγIIA receptor–induced phagocytosis

Superoxide produced by the phagocyte reduced nicotinamide adenine dinucleotide phosphate (NADPH) oxidase is essential for host defense. Enzyme activation requires translocation of p67(phox), p47(phox), and Rac-GTP to flavocytochrome b (558) in phagocyte membranes. To examine the regulation of phagoc...

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Hlavní autoři: Suh, Chang-Il, Stull, Natalie D., Li, Xing Jun, Tian, Wei, Price, Marianne O., Grinstein, Sergio, Yaffe, Michael B., Atkinson, Simon, Dinauer, Mary C.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2006
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2118377/
https://ncbi.nlm.nih.gov/pubmed/16880255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20052085
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