Cooperation of p40(phox) with p47(phox) for Nox2-based NADPH Oxidase Activation during Fcγ Receptor (FcγR)-mediated Phagocytosis: MECHANISM FOR ACQUISITION OF p40(phox) PHOSPHATIDYLINOSITOL 3-PHOSPHATE (PI(3)P) BINDING

During activation of the phagocyte (Nox2-based) NADPH oxidase, the cytoplasmic Phox complex (p47(phox)-p67(phox)-p40(phox)) translocates and associates with the membrane-spanning flavocytochrome b(558). It is unclear where (in cytoplasm or on membranes), when (before or after assembly), and how p40(...

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Detalles Bibliográficos
Main Authors: Ueyama, Takehiko, Nakakita, Junya, Nakamura, Takashi, Kobayashi, Takeshi, Kobayashi, Toshihiro, Son, Jeonghyun, Sakuma, Megumi, Sakaguchi, Hirofumi, Leto, Thomas L., Saito, Naoaki
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3220462/
https://ncbi.nlm.nih.gov/pubmed/21956105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.237289
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