A Regulated Adaptor Function of p40(phox): Distinct p67(phox) Membrane Targeting by p40(phox) and by p47(phox)

In the phagocytic cell, NADPH oxidase (Nox2) system, cytoplasmic regulators (p47(phox), p67(phox), p40(phox), and Rac) translocate and associate with the membrane-spanning flavocytochrome b(558), leading to activation of superoxide production. We examined membrane targeting of phox proteins and expl...

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Bibliografiske detaljer
Main Authors: Ueyama, Takehiko, Tatsuno, Toshihiko, Kawasaki, Takumi, Tsujibe, Satoshi, Shirai, Yasuhito, Sumimoto, Hideki, Leto, Thomas L., Saito, Naoaki
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2007
Fag:
Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783789/
https://ncbi.nlm.nih.gov/pubmed/17122360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0731
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