Protein-Folding Homeostasis in the Endoplasmic Reticulum and Nutritional Regulation

by Ron, David, Harding, Heather P.
Published 2012

Translation reinitiation at alternative open reading frames regulates gene expression in an integrated stress response

by Lu, Phoebe D., Harding, Heather P., Ron, David
Published 2004

Uncoupling Proteostasis and Development in Vitro with a Small Molecule Inhibitor of the Pancreatic Endoplasmic Reticulum Kinase, PERK

by Harding, Heather P., Zyryanova, Alisa F., Ron, David
Published 2012

Endoplasmic reticulum stress modulates the response of myelinating oligodendrocytes to the immune cytokine interferon-γ

by Lin, Wensheng, Harding, Heather P., Ron, David, Popko, Brian
Published 2005

Feedback Inhibition of the Unfolded Protein Response by GADD34-Mediated Dephosphorylation of eIF2α

by Novoa, Isabel, Zeng, Huiqing, Harding, Heather P., Ron, David
Published 2001

A Polyphenol Rich Muscadine Grape Extract Reduces Triple Negative Breast Cancer Cell Migration in Association with Changes in Cell Morphology and Motility-Related Proteins

by Gallagher, Patricia, Collard, Marianne, Brown-Harding, Heather, Tallant, Elisabeth
Published in Curr Dev Nutr (2020)

A membrane transporter determines the spectrum of activity of a potent platinum–acridine hybrid anticancer agent

by Yao, Xiyuan, Watkins, Noah H., Brown-Harding, Heather, Bierbach, Ulrich
Published in Sci Rep (2020)

Cargo receptor-assisted endoplasmic reticulum export of pathogenic α1-antitrypsin polymers

by Ordóñez, Adriana, Harding, Heather P., Marciniak, Stefan J., Ron, David
Published in Cell Rep (2021)

De-phosphorylation of translation initiation factor 2α (eIF2α) enhances glucose tolerance and attenuates hepato-steatosis in mice

by Oyadomari, Seiichi, Harding, Heather P., Zhang, Yuhong, Oyadomari, Miho, Ron, David
Published 2008

Ubiquitin-Like Protein 5 Positively Regulates Chaperone Gene Expression in the Mitochondrial Unfolded Protein Response

by Benedetti, Cristina, Haynes, Cole M., Yang, Yun, Harding, Heather P., Ron, David
Published 2006

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

by Zito, Ester, Chin, King-Tung, Blais, Jaime, Harding, Heather P., Ron, David
Published 2010

ERO1-β, a pancreas-specific disulfide oxidase, promotes insulin biogenesis and glucose homeostasis

by Zito, Ester, Chin, King-Tung, Blais, Jaime, Harding, Heather P., Ron, David
Published 2010

CHOP-Dependent Stress-Inducible Expression of a Novel Form of Carbonic Anhydrase VI

by Sok, John, Wang, Xiao-Zhong, Batchvarova, Nikoleta, Kuroda, Masahiko, Harding, Heather, Ron, David
Published 1999

Stress-induced gene expression requires programmed recovery from translational repression

by Novoa, Isabel, Zhang, Yuhong, Zeng, Huiqing, Jungreis, Rivka, Harding, Heather P., Ron, David
Published 2003

Activation-dependent substrate recruitment by the eukaryotic translation initiation factor 2 kinase PERK

by Marciniak, Stefan J., Garcia-Bonilla, Lidia, Hu, Junjie, Harding, Heather P., Ron, David
Published 2006

Translation attenuation by PERK balances ER glycoprotein synthesis with lipid-linked oligosaccharide flux

by Shang, Jie, Gao, Ningguo, Kaufman, Randal J., Ron, David, Harding, Heather P., Lehrman, Mark A.
Published 2007

Inhibition of a constitutive translation initiation factor 2α phosphatase, CReP, promotes survival of stressed cells

by Jousse, Céline, Oyadomari, Seiichi, Novoa, Isabel, Lu, Phoebe, Zhang, Yuhong, Harding, Heather P., Ron, David
Published 2003

Enhanced Integrated Stress Response Promotes Myelinating Oligodendrocyte Survival in Response to Interferon-γ

by Lin, Wensheng, Kunkler, Phillip E., Harding, Heather P., Ron, David, Kraig, Richard P., Popko, Brian
Published 2008

Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development

by Harding, Heather P., Zhang, Yuhong, Scheuner, Donalyn, Chen, Jane-Jane, Kaufman, Randal J., Ron, David
Published 2009

PERK Activation Preserves the Viability and Function of Remyelinating Oligodendrocytes in Immune-Mediated Demyelinating Diseases

by Lin, Yifeng, Huang, Guangcun, Jamison, Stephanie, Li, Jin, Harding, Heather P., Ron, David, Lin, Wensheng
Published 2014