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A membrane transporter determines the spectrum of activity of a potent platinum–acridine hybrid anticancer agent

Cytotoxic drugs that are mechanistically distinct from current chemotherapies are attractive components of personalized combination regimens for combatting aggressive forms of cancer. To gain insight into the cellular mechanism of a potent platinum–acridine anticancer agent (compound 1), a correlati...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yao, Xiyuan, Watkins, Noah H., Brown-Harding, Heather, Bierbach, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7494928/
https://ncbi.nlm.nih.gov/pubmed/32939009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72099-z
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