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Inhibition of DNA Synthesis by a Platinum–Acridine Hybrid Agent Leads to Potent Cell Kill in Nonsmall Cell Lung Cancer
[Image: see text] The platinum–acridine anticancer agent [PtCl(en)(LH)](NO(3))(2) (1) [en = ethane-1,2-diamine, LH = N-(2-(acridin-9-ylamino)ethyl)-N-methylpropionimidamide, acridinium cation] and the clinical drug cisplatin were studied in chemoresistant nonsmall cell lung cancer (NSCLC) cell lines...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Chemical Society
2011
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| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3274750/ https://ncbi.nlm.nih.gov/pubmed/22328962 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml2001888 |
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