Gold(I) Analogues of a Platinum–Acridine Antitumor Agent are only Moderately Cytotoxic but Show Potent Activity Against Mycobacterium Tuberculosis

A series of cationic gold(I) complexes containing 1-[2-(acridin-9-ylamino)ethyl]-1,3-dimethylthiourea (1), [AuL(1)](n+) (where L is Cl(−), Br(-), SCN(−), PEt(3), PPh(3), or 1), derived from a class of analogous platinum(II) antitumor agents, has been synthesized. Unlike platinum, gold does not form...

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Hlavní autoři: Eiter, Lauren C., Hall, Nathan W., Day, Cynthia S., Saluta, Gilda, Kucera, Gregory L., Bierbach, Ulrich
Médium: Artigo
Jazyk:Inglês
Vydáno: 2009
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176588/
https://ncbi.nlm.nih.gov/pubmed/19803526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm9012856
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