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Unusual Reactivity of a Potent Platinum–Acridine Hybrid Antitumor Agent

[Image: see text] The formation of unusual seven-membered, sterically overloaded chelates [Pt(en)(L/L′)](NO(3))(2) (4a/4b) from the corresponding potent hybrid antitumor agents [PtCl(en)(LH/L′H)](NO(3))(2) (3a/3b) is described, where en is ethane-1,2-diamine and L(H) and L′(H) are (protonated) N-(2-...

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Detalhes bibliográficos
Main Authors: Graham, Leigh A., Wilson, Gary M., West, Tiffany K., Day, Cynthia S., Kucera, Gregory L., Bierbach, Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2011
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173770/
https://ncbi.nlm.nih.gov/pubmed/21927647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml200104h
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