Laddar...
A Non-Cross-Linking Platinum–Acridine Agent with Potent Activity in Non-Small Cell Lung Cancer
The cytotoxic complex, [PtCl(Am)(2)(ACRAMTU)](NO(3))(2) (1) ((Am)(2) = ethane-1,2-diamine, en; ACRAMTU = 1-[2-(acridin-9-ylamino)ethyl]-1,3-dimethylthiourea), is a dual platinating/intercalating DNA binder that, unlike clinical platinum agents, does not induce DNA cross-links. Here, we demonstrate t...
Sparad:
| Huvudupphovsmän: | , , , , , , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2008
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2743007/ https://ncbi.nlm.nih.gov/pubmed/19012390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm800900g |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|