PERK Activation Preserves the Viability and Function of Remyelinating Oligodendrocytes in Immune-Mediated Demyelinating Diseases

Remyelination occurs in multiple sclerosis (MS) lesions but is generally considered to be insufficient. One of the major challenges in MS research is to understand the causes of remyelination failure and to identify therapeutic targets that promote remyelination. Activation of pancreatic endoplasmic...

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Hlavní autoři: Lin, Yifeng, Huang, Guangcun, Jamison, Stephanie, Li, Jin, Harding, Heather P., Ron, David, Lin, Wensheng
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2014
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906495/
https://ncbi.nlm.nih.gov/pubmed/24269558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.10.009
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