PERK Activation Preserves the Viability and Function of Remyelinating Oligodendrocytes in Immune-Mediated Demyelinating Diseases

Remyelination occurs in multiple sclerosis (MS) lesions but is generally considered to be insufficient. One of the major challenges in MS research is to understand the causes of remyelination failure and to identify therapeutic targets that promote remyelination. Activation of pancreatic endoplasmic...

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Detalhes bibliográficos
Main Authors: Lin, Yifeng, Huang, Guangcun, Jamison, Stephanie, Li, Jin, Harding, Heather P., Ron, David, Lin, Wensheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2014
Assuntos:
Regular Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3906495/
https://ncbi.nlm.nih.gov/pubmed/24269558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2013.10.009
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