Impaired Eukaryotic Translation Initiation Factor 2B Activity Specifically in Oligodendrocytes Reproduces the Pathology of Vanishing White Matter Disease in Mice

Vanishing white matter disease (VWMD) is an inherited autosomal-recessive hypomyelinating disease caused by mutations in eukaryotic translation initiation factor 2B (eIF2B). eIF2B mutations predominantly affect the brain white matter, and the characteristic features of VWMD pathology include myelin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Lin, Yifeng, Pang, Xiaosha, Huang, Guangcun, Jamison, Stephanie, Fang, Jingye, Harding, Heather P., Ron, David, Lin, Wensheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2014
Aiheet:
Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4152613/
https://ncbi.nlm.nih.gov/pubmed/25186761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1373-14.2014
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia