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Axonal abnormalities in vanishing white matter

OBJECTIVE: We aimed to study the occurrence and development of axonal pathology and the influence of astrocytes in vanishing white matter. METHODS: Axons and myelin were analyzed using electron microscopy and immunohistochemistry on Eif2b4 and Eif2b5 single‐ and double‐mutant mice and patient brain...

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Dettagli Bibliografici
Pubblicato in:Ann Clin Transl Neurol
Autori principali: Klok, Melanie D., Bugiani, Marianna, de Vries, Sharon I., Gerritsen, Wouter, Breur, Marjolein, van der Sluis, Sophie, Heine, Vivi M., Kole, Maarten H. P., Baron, Wia, van der Knaap, Marjo S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899913/
https://ncbi.nlm.nih.gov/pubmed/29687020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.540
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