Axonal abnormalities in vanishing white matter

OBJECTIVE: We aimed to study the occurrence and development of axonal pathology and the influence of astrocytes in vanishing white matter. METHODS: Axons and myelin were analyzed using electron microscopy and immunohistochemistry on Eif2b4 and Eif2b5 single‐ and double‐mutant mice and patient brain...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Klok, Melanie D., Bugiani, Marianna, de Vries, Sharon I., Gerritsen, Wouter, Breur, Marjolein, van der Sluis, Sophie, Heine, Vivi M., Kole, Maarten H. P., Baron, Wia, van der Knaap, Marjo S.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899913/
https://ncbi.nlm.nih.gov/pubmed/29687020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.540
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